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Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone

A range of severe human diseases called ciliopathies is caused by the dysfunction of primary cilia. Primary cilia are cytoplasmic protrusions consisting of the basal body (BB), the axoneme, and the transition zone (TZ). The BB is a modified mother centriole from which the axoneme, the microtubule-ba...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Wiegering, Antonia, Dildrop, Renate, Vesque, Christine, Khanna, Hemant, Schneider-Maunoury, Sylvie, Gerhardt, Christoph
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108517/
https://ncbi.nlm.nih.gov/pubmed/33625872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-03-0190
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