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Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone

A range of severe human diseases called ciliopathies is caused by the dysfunction of primary cilia. Primary cilia are cytoplasmic protrusions consisting of the basal body (BB), the axoneme, and the transition zone (TZ). The BB is a modified mother centriole from which the axoneme, the microtubule-ba...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Wiegering, Antonia, Dildrop, Renate, Vesque, Christine, Khanna, Hemant, Schneider-Maunoury, Sylvie, Gerhardt, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108517/
https://ncbi.nlm.nih.gov/pubmed/33625872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-03-0190
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