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Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone

A range of severe human diseases called ciliopathies is caused by the dysfunction of primary cilia. Primary cilia are cytoplasmic protrusions consisting of the basal body (BB), the axoneme, and the transition zone (TZ). The BB is a modified mother centriole from which the axoneme, the microtubule-ba...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Wiegering, Antonia, Dildrop, Renate, Vesque, Christine, Khanna, Hemant, Schneider-Maunoury, Sylvie, Gerhardt, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108517/
https://ncbi.nlm.nih.gov/pubmed/33625872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-03-0190
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