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Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome
Pseudogenes are gene copies presumed to mainly be functionless relics of evolution due to acquired deleterious mutations or transcriptional silencing. Using deep full-length PacBio cDNA sequencing of normal human tissues and cancer cell lines, we identify here hundreds of novel transcribed pseudogen...
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| Pubblicato in: | Genome Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8108447/ https://ncbi.nlm.nih.gov/pubmed/33971925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02369-0 |
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