Myeloid-derived suppressor cells regulate the immunosuppressive functions of PD-1(−)PD-L1(+) Bregs through PD-L1/PI3K/AKT/NF-κB axis in breast cancer

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid cells that are closely related to tumor immune escape, but the mechanism by which MDSCs regulate B cells has not been elucidated. Our previous studies revealed that breast cancer-derived MDSCs could induce a group of PD-1(...

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Publicado no:Cell Death Dis
Main Authors: Liu, Min, Wei, Feng, Wang, Jian, Yu, Wenwen, Shen, Meng, Liu, Ting, Zhang, Dong, Wang, Yang, Ren, Xiubao, Sun, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107179/
https://ncbi.nlm.nih.gov/pubmed/33967272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03745-1
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