Early Activation of Myeloid-Derived Suppressor Cells Participate in Sepsis-Induced Immune Suppression via PD-L1/PD-1 Axis

Background: Myeloid derived suppressor cells (MDSCs) have been reported to keep elevating during sepsis. The current study was performed to investigate the immunosuppressive effect of MDSCs and their subsets with the underlying mechanisms. Methods: The immunosuppressive status was manifested by the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ruan, Wei-Shuyi, Feng, Meng-Xiao, Xu, Jia, Xu, Ying-Ge, Song, Cong-Ying, Lin, Li-Ying, Li, Li, Lu, Yuan-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347749/
https://ncbi.nlm.nih.gov/pubmed/32719675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01299
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