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TRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability

Resistance to chemotherapy remains the major cause of treatment failure in patients with colorectal cancer (CRC). Here, we identified TRIM25 as an epigenetic regulator of oxaliplatin (OXA) resistance in CRC. The level of TRIM25 in OXA-resistant patients who experienced recurrence during the follow-u...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Zhou, Sha, Peng, Jianhong, Xiao, Liuniu, Zhou, Caixia, Fang, Yujing, Ou, Qingjian, Qin, Jiayi, Liu, Mengzhong, Pan, Zhizhong, Hou, Zhenlin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106682/
https://ncbi.nlm.nih.gov/pubmed/33966039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03734-4
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