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TRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability

Resistance to chemotherapy remains the major cause of treatment failure in patients with colorectal cancer (CRC). Here, we identified TRIM25 as an epigenetic regulator of oxaliplatin (OXA) resistance in CRC. The level of TRIM25 in OXA-resistant patients who experienced recurrence during the follow-u...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhou, Sha, Peng, Jianhong, Xiao, Liuniu, Zhou, Caixia, Fang, Yujing, Ou, Qingjian, Qin, Jiayi, Liu, Mengzhong, Pan, Zhizhong, Hou, Zhenlin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106682/
https://ncbi.nlm.nih.gov/pubmed/33966039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03734-4
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