TRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability

Resistance to chemotherapy remains the major cause of treatment failure in patients with colorectal cancer (CRC). Here, we identified TRIM25 as an epigenetic regulator of oxaliplatin (OXA) resistance in CRC. The level of TRIM25 in OXA-resistant patients who experienced recurrence during the follow-u...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Zhou, Sha, Peng, Jianhong, Xiao, Liuniu, Zhou, Caixia, Fang, Yujing, Ou, Qingjian, Qin, Jiayi, Liu, Mengzhong, Pan, Zhizhong, Hou, Zhenlin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106682/
https://ncbi.nlm.nih.gov/pubmed/33966039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03734-4
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