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Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis

Comparative sequence analysis has enabled the annotation of millions of genes from organisms across the evolutionary tree. However, this approach has inherently biased the annotation of phylogenetically ubiquitous, rather than species-specific, functions. The ecologically unusual pathogen Mycobacter...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Black, Katherine A., Duan, Lijun, Mandyoli, Lungelo, Selbach, Bruna P., Xu, Weizhen, Ehrt, Sabine, Sacchettini, James C., Rhee, Kyu Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105722/
https://ncbi.nlm.nih.gov/pubmed/33950161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191957
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