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Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis

Comparative sequence analysis has enabled the annotation of millions of genes from organisms across the evolutionary tree. However, this approach has inherently biased the annotation of phylogenetically ubiquitous, rather than species-specific, functions. The ecologically unusual pathogen Mycobacter...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Black, Katherine A., Duan, Lijun, Mandyoli, Lungelo, Selbach, Bruna P., Xu, Weizhen, Ehrt, Sabine, Sacchettini, James C., Rhee, Kyu Y.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105722/
https://ncbi.nlm.nih.gov/pubmed/33950161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191957
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