Inhibition of peptidoglycan biosynthesis by ramoplanin.

Ramoplanin, a new lipoglycopeptide antibiotic, inhibits cell wall peptidoglycan biosynthesis in gram-positive bacteria. In both Staphylococcus aureus and Bacillus megaterium, UDP-N-acetylmuramyl-pentapeptides (UDP-MurNAc-pentapeptides) accumulated at concentrations of ramoplanin close to the MIC, in...

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Bibliographic Details
Main Authors: Somner, E A, Reynolds, P E
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC171607/
https://ncbi.nlm.nih.gov/pubmed/2334153
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