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Molecular dynamics simulations of Piezo1 channel opening by increases in membrane tension
Piezo1 is a mechanosensitive channel involved in many cellular functions and responsible for sensing shear stress and pressure forces in cells. Piezo1 has a unique trilobed topology with a curved membrane region in the closed state. It has been suggested that upon activation Piezo1 adopts a flattene...
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| Опубликовано в: : | Biophys J |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8105709/ https://ncbi.nlm.nih.gov/pubmed/33582135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.006 |
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