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Molecular Simulations of Intact Anion Exchanger 1 Reveal Specific Domain and Lipid Interactions

Anion exchanger 1 (AE1) is responsible for the exchange of bicarbonate and chloride across the erythrocyte plasma membrane. Human AE1 consists of a cytoplasmic and a membrane domain joined by a 33-residue flexible linker. Crystal structures of the individual domains have been determined, but the int...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: De Vecchis, Dario, Reithmeier, Reinhart A.F., Kalli, Antreas C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818359/
https://ncbi.nlm.nih.gov/pubmed/31540709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.029
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