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Molecular dynamics simulations of Piezo1 channel opening by increases in membrane tension
Piezo1 is a mechanosensitive channel involved in many cellular functions and responsible for sensing shear stress and pressure forces in cells. Piezo1 has a unique trilobed topology with a curved membrane region in the closed state. It has been suggested that upon activation Piezo1 adopts a flattene...
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| Publicado no: | Biophys J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8105709/ https://ncbi.nlm.nih.gov/pubmed/33582135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.006 |
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