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Production of recombinant human G-CSF from non-classical inclusion bodies in Escherichia coli

Recombinant granulocyte colony–stimulating factor (G-CSF) protein produced in Escherichia coli has been widely used for the treatment of neutropenia induced by chemotherapy for decades. In E. coli cells, G-CSF is usually expressed as inactive inclusion bodies, which requires costly and inefficient d...

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Библиографические подробности
Опубликовано в: :Braz J Microbiol
Главные авторы: Trinh, Nguyen Thi My, Thuoc, Tran Linh, Thao, Dang Thi Phuong
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105469/
https://ncbi.nlm.nih.gov/pubmed/33483893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s42770-020-00413-y
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