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GPIbα is the driving force of hepatic thrombopoietin generation

Thrombopoietin (TPO), a glycoprotein hormone produced predominantly in the liver, plays important roles in the hematopoietic stem cell (HSC) niche, and is essential for megakaryopoiesis and platelet generation. Long‐standing understanding proposes that TPO is constitutively produced by hepatocytes,...

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Bibliografiske detaljer
Udgivet i:Res Pract Thromb Haemost
Main Authors: Karakas, Danielle, Xu, Miao, Ni, Heyu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105161/
https://ncbi.nlm.nih.gov/pubmed/33977209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12506
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