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HIV-1 Nef-Induced Secretion of the Proinflammatory Protease TACE into Extracellular Vesicles Is Mediated by Raf-1 and Can Be Suppressed by Clinical Protein Kinase Inhibitors

Chronic immune activation is an important driver of human immunodeficiency virus type 1 (HIV-1) pathogenesis and has been associated with the presence of tumor necrosis factor-α converting enzyme (TACE) in extracellular vesicles (EVs) circulating in infected individuals. We have recently shown that...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Virol
मुख्य लेखकों: Zhao, Zhe, Fagerlund, Riku, Baur, Andreas S., Saksela, Kalle
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8104104/
https://ncbi.nlm.nih.gov/pubmed/33597213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00180-21
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