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MC159 of Molluscum Contagiosum Virus Suppresses Autophagy by Recruiting Cellular SH3BP4 via an SH3 Domain-Mediated Interaction

MC159 is a viral FLIP (FLICE inhibitory protein) encoded by the molluscum contagiosum virus (MCV) enabling MCV to evade antiviral immunity and to establish persistent infections in humans. Here, we show that MC159 contains a functional SH3 binding motif, which mediates avid and selective binding to...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Schmotz, Constanze, Uğurlu, Hasan, Vilen, Silja, Shrestha, Subhash, Fagerlund, Riku, Saksela, Kalle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498068/
https://ncbi.nlm.nih.gov/pubmed/30842330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01613-18
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