Binding of FADD and Caspase-8 to Molluscum Contagiosum Virus MC159 v-FLIP Is Not Sufficient for Its Antiapoptotic Function

Molluscum contagiosum virus (MCV), a member of the human poxvirus family, encodes the MC159 protein that inhibits Fas-, tumor necrosis factor (TNF)-, and TNF-related apoptosis-inducing ligant (TRAIL)-induced apoptosis. We used site-directed mutagenesis to change charged or hydrophobic amino acid res...

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Detalhes bibliográficos
Main Authors: Garvey, Tara L., Bertin, John, Siegel, Richard M., Wang, Guang-hua, Lenardo, Michael J., Cohen, Jeffrey I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136828/
https://ncbi.nlm.nih.gov/pubmed/11752160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.697-706.2002
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