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Functional Comparison of Molluscum Contagiosum Virus vFLIP MC159 with Murine Cytomegalovirus M36/vICA and M45/vIRA Proteins

Molluscum contagiosum virus (MCV) gene MC159 encodes a viral FLICE inhibitory protein (vFLIP) that inhibits caspase-8-mediated apoptosis. The MC159 protein was also reported to inhibit programmed necrosis (necroptosis) and modulate NF-κB activation by interacting with RIP1 and NEMO. The importance o...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hüttmann, Julia, Krause, Eva, Schommartz, Tim, Brune, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810660/
https://ncbi.nlm.nih.gov/pubmed/26719271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02729-15
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