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MC159 of Molluscum Contagiosum Virus Suppresses Autophagy by Recruiting Cellular SH3BP4 via an SH3 Domain-Mediated Interaction

MC159 is a viral FLIP (FLICE inhibitory protein) encoded by the molluscum contagiosum virus (MCV) enabling MCV to evade antiviral immunity and to establish persistent infections in humans. Here, we show that MC159 contains a functional SH3 binding motif, which mediates avid and selective binding to...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Schmotz, Constanze, Uğurlu, Hasan, Vilen, Silja, Shrestha, Subhash, Fagerlund, Riku, Saksela, Kalle
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498068/
https://ncbi.nlm.nih.gov/pubmed/30842330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01613-18
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