SARS-CoV-2 Triggers an MDA-5-Dependent Interferon Response Which Is Unable To Control Replication in Lung Epithelial Cells

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of coronavirus disease 19 (COVID-19), which ranges from mild respiratory symptoms to acute respiratory distress syndrome, and death in the most severe cases. Immune dysregulation with altered innate cytokine response...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Rebendenne, Antoine, Chaves Valadão, Ana Luiza, Tauziet, Marine, Maarifi, Ghizlane, Bonaventure, Boris, McKellar, Joe, Planès, Rémi, Nisole, Sébastien, Arnaud-Arnould, Mary, Moncorgé, Olivier, Goujon, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103705/
https://ncbi.nlm.nih.gov/pubmed/33514628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02415-20
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