SARS-CoV-2 Triggers an MDA-5-Dependent Interferon Response Which Is Unable To Control Replication in Lung Epithelial Cells

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of coronavirus disease 19 (COVID-19), which ranges from mild respiratory symptoms to acute respiratory distress syndrome, and death in the most severe cases. Immune dysregulation with altered innate cytokine response...

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Udgivet i:J Virol
Main Authors: Rebendenne, Antoine, Chaves Valadão, Ana Luiza, Tauziet, Marine, Maarifi, Ghizlane, Bonaventure, Boris, McKellar, Joe, Planès, Rémi, Nisole, Sébastien, Arnaud-Arnould, Mary, Moncorgé, Olivier, Goujon, Caroline
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Cellular Response to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103705/
https://ncbi.nlm.nih.gov/pubmed/33514628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02415-20
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