CAGE-Seq Reveals that HIV-1 Latent Infection Does Not Trigger Unique Cellular Responses in a Jurkat T Cell Model

The cure for HIV-1 is currently stalled by our inability to specifically identify and target latently infected cells. HIV-1 viral RNA/DNA or viral proteins are recognized by cellular mechanisms and induce interferon responses in virus-producing cells, but changes in latently infected cells remain un...

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Vydáno v:J Virol
Hlavní autoři: Matsui, Hiroyuki, Shirakawa, Kotaro, Konishi, Yoshinobu, Hirabayashi, Shigeki, Sarca, Anamaria Daniela, Fukuda, Hirofumi, Nomura, Ryosuke, Stanford, Emani, Horisawa, Yoshihito, Kazuma, Yasuhiro, Matsumoto, Tadahiko, Yamazaki, Hiroyuki, Murakawa, Yasuhiro, Battivelli, Emilie, Verdin, Eric, Koyanagi, Yoshio, Takaori-Kondo, Akifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103700/
https://ncbi.nlm.nih.gov/pubmed/33504604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02394-20
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