Respiratory Syncytial Virus Activates Rab5a To Suppress IRF1-Dependent Lambda Interferon Production, Subverting the Antiviral Defense of Airway Epithelial Cells

The limited antiviral options and lack of an effective vaccine against human respiratory syncytial virus (RSV) highlight the need for a novel antiviral therapy. One alternative is to identify and target the host factors required for viral infection. Here, using RNA interference to knock down Rab pro...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Mo, Shi, Tang, Wei, Xie, Jun, Chen, Sisi, Ren, Luo, Zang, Na, Xie, Xiaohong, Deng, Yu, Gao, Leiqiong, Liu, Enmei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2021
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103688/
https://ncbi.nlm.nih.gov/pubmed/33504607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02333-20
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