Respiratory Syncytial Virus Activates Rab5a To Suppress IRF1-Dependent Lambda Interferon Production, Subverting the Antiviral Defense of Airway Epithelial Cells

The limited antiviral options and lack of an effective vaccine against human respiratory syncytial virus (RSV) highlight the need for a novel antiviral therapy. One alternative is to identify and target the host factors required for viral infection. Here, using RNA interference to knock down Rab pro...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mo, Shi, Tang, Wei, Xie, Jun, Chen, Sisi, Ren, Luo, Zang, Na, Xie, Xiaohong, Deng, Yu, Gao, Leiqiong, Liu, Enmei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103688/
https://ncbi.nlm.nih.gov/pubmed/33504607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02333-20
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