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Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

Viruses suppress host responses to increase infection, and understanding these mechanisms has provided insights into cellular signaling and led to novel therapies. Many viruses (e.g., Influenza virus, Rhinovirus [RV], Cytomegalovirus, Epstein-Barr virus, and Hepatitis C virus) activate epithelial ep...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ueki, Iris F., Min-Oo, Gundula, Kalinowski, April, Ballon-Landa, Eric, Lanier, Lewis L., Nadel, Jay A., Koff, Jonathan L.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782052/
https://ncbi.nlm.nih.gov/pubmed/23999497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121401
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