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Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

Viruses suppress host responses to increase infection, and understanding these mechanisms has provided insights into cellular signaling and led to novel therapies. Many viruses (e.g., Influenza virus, Rhinovirus [RV], Cytomegalovirus, Epstein-Barr virus, and Hepatitis C virus) activate epithelial ep...

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Detalhes bibliográficos
Main Authors: Ueki, Iris F., Min-Oo, Gundula, Kalinowski, April, Ballon-Landa, Eric, Lanier, Lewis L., Nadel, Jay A., Koff, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782052/
https://ncbi.nlm.nih.gov/pubmed/23999497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121401
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