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Lipid Nanoparticle-Mediated Lymphatic Delivery of Immunostimulatory Nucleic Acids
Lymphatic delivery of a vaccine can be achieved using a dendritic cell (DC)-targeted delivery system that can cause DC to migrate to lymph nodes upon activation by an adjuvant. Here, we designed a mannose-modified cationic lipid nanoparticle (M-NP) to deliver the nucleic acid adjuvant, polyinosinic:...
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| Publicado no: | Pharmaceutics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8103501/ https://ncbi.nlm.nih.gov/pubmed/33916667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040490 |
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