Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery

The specific activation of Toll-like receptors (TLRs) has potential utility for a variety of therapeutic indications including antiviral immunotherapy and as vaccine adjuvants. TLR7 and TLR 8 may be activated by their native ligands, single-stranded RNA, or by small molecules of the imidazoquinoline...

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Dettagli Bibliografici
Autori principali: Nguyen, David N., Mahon, Kerry P., Chikh, Ghania, Kim, Phillip, Chung, Hattie, Vicari, Alain P., Love, Kevin T., Goldberg, Michael, Chen, Steve, Krieg, Arthur M., Chen, Jianzhu, Langer, Robert, Anderson, Daniel G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325698/
https://ncbi.nlm.nih.gov/pubmed/22421433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121423109
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