Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery

The specific activation of Toll-like receptors (TLRs) has potential utility for a variety of therapeutic indications including antiviral immunotherapy and as vaccine adjuvants. TLR7 and TLR 8 may be activated by their native ligands, single-stranded RNA, or by small molecules of the imidazoquinoline...

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Dades bibliogràfiques
Autors principals: Nguyen, David N., Mahon, Kerry P., Chikh, Ghania, Kim, Phillip, Chung, Hattie, Vicari, Alain P., Love, Kevin T., Goldberg, Michael, Chen, Steve, Krieg, Arthur M., Chen, Jianzhu, Langer, Robert, Anderson, Daniel G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325698/
https://ncbi.nlm.nih.gov/pubmed/22421433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121423109
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