Disease Status–Dependent Drug–Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and Gardenia jasminoides J. Ellis

Concurrent use of simvastatin (SV) and Gardenia jasminoides J. Ellis (GJ) was adopted in patients with multi-morbidity, such as stroke rehabilitation patients with NASH. Although hepatotoxicity has been reported in both of them and NASH could alter the pharmacokinetics of drugs/herbs, the interactio...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Li, Ziwei, Lyu, Yuanfeng, Zhao, Jiajia, Li, Dan, Lin, Zhixiu, To, Kenneth Kin Wah, Yan, Xiaoyu, Zuo, Zhong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103205/
https://ncbi.nlm.nih.gov/pubmed/33967756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.622040
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