Disease Status–Dependent Drug–Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and Gardenia jasminoides J. Ellis

Concurrent use of simvastatin (SV) and Gardenia jasminoides J. Ellis (GJ) was adopted in patients with multi-morbidity, such as stroke rehabilitation patients with NASH. Although hepatotoxicity has been reported in both of them and NASH could alter the pharmacokinetics of drugs/herbs, the interactio...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Ziwei, Lyu, Yuanfeng, Zhao, Jiajia, Li, Dan, Lin, Zhixiu, To, Kenneth Kin Wah, Yan, Xiaoyu, Zuo, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103205/
https://ncbi.nlm.nih.gov/pubmed/33967756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.622040
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