Disease Status–Dependent Drug–Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and Gardenia jasminoides J. Ellis

Concurrent use of simvastatin (SV) and Gardenia jasminoides J. Ellis (GJ) was adopted in patients with multi-morbidity, such as stroke rehabilitation patients with NASH. Although hepatotoxicity has been reported in both of them and NASH could alter the pharmacokinetics of drugs/herbs, the interactio...

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Vydáno v:Front Pharmacol
Hlavní autoři: Li, Ziwei, Lyu, Yuanfeng, Zhao, Jiajia, Li, Dan, Lin, Zhixiu, To, Kenneth Kin Wah, Yan, Xiaoyu, Zuo, Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103205/
https://ncbi.nlm.nih.gov/pubmed/33967756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.622040
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