Rqc1 and other yeast proteins containing highly positively charged sequences are not targets of the RQC complex

Previous work has suggested that highly positively charged protein segments coded by rare codons or poly (A) stretches induce ribosome stalling and translational arrest through electrostatic interactions with the negatively charged ribosome exit tunnel, leading to inefficient elongation. This arrest...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Barros, Géssica C., Requião, Rodrigo D., Carneiro, Rodolfo L., Masuda, Claudio A., Moreira, Mariana H., Rossetto, Silvana, Domitrovic, Tatiana, Palhano, Fernando L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2021
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102910/
https://ncbi.nlm.nih.gov/pubmed/33774050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100586
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