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Increased ribosome density associated to positively charged residues is evident in ribosome profiling experiments performed in the absence of translation inhibitors

It has been proposed that polybasic peptides cause slower movement of ribosomes through an electrostatic interaction with the highly negative ribosome exit tunnel. Ribosome profiling data—the sequencing of short ribosome-bound fragments of mRNA—is a powerful tool for the analysis of mRNA translation...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Requião, Rodrigo D., de Souza, Henrique José Araujo, Rossetto, Silvana, Domitrovic, Tatiana, Palhano, Fernando L.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962802/
https://ncbi.nlm.nih.gov/pubmed/27064519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1172755
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