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Increased ribosome density associated to positively charged residues is evident in ribosome profiling experiments performed in the absence of translation inhibitors

It has been proposed that polybasic peptides cause slower movement of ribosomes through an electrostatic interaction with the highly negative ribosome exit tunnel. Ribosome profiling data—the sequencing of short ribosome-bound fragments of mRNA—is a powerful tool for the analysis of mRNA translation...

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Detalles Bibliográficos
Publicado en:RNA Biol
Main Authors: Requião, Rodrigo D., de Souza, Henrique José Araujo, Rossetto, Silvana, Domitrovic, Tatiana, Palhano, Fernando L.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962802/
https://ncbi.nlm.nih.gov/pubmed/27064519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1172755
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