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The Molecular Functions of MeCP2 in Rett Syndrome Pathology

MeCP2 protein, encoded by the MECP2 gene, binds to DNA and affects transcription. Outside of this activity the true range of MeCP2 function is still not entirely clear. As MECP2 gene mutations cause the neurodevelopmental disorder Rett syndrome in 1 in 10,000 female births, much of what is known abo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Sharifi, Osman, Yasui, Dag H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102816/
https://ncbi.nlm.nih.gov/pubmed/33968128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.624290
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