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The Molecular Functions of MeCP2 in Rett Syndrome Pathology

MeCP2 protein, encoded by the MECP2 gene, binds to DNA and affects transcription. Outside of this activity the true range of MeCP2 function is still not entirely clear. As MECP2 gene mutations cause the neurodevelopmental disorder Rett syndrome in 1 in 10,000 female births, much of what is known abo...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Sharifi, Osman, Yasui, Dag H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102816/
https://ncbi.nlm.nih.gov/pubmed/33968128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.624290
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