Melatonin delays ovarian aging in mice by slowing down the exhaustion of ovarian reserve

Studies have shown that melatonin (MLT) can delay ovarian aging, but the mechanism has not been fully elucidated. Here we show that granulosa cells isolated from mice follicles can synthesize MLT; the addition of MLT in ovary culture system inhibited follicle activation and growth; In vivo experimen...

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Detaylı Bibliyografya
Yayımlandı:Commun Biol
Asıl Yazarlar: Yang, Chan, Liu, Qinghua, Chen, Yingjun, Wang, Xiaodong, Ran, Zaohong, Fang, Fang, Xiong, Jiajun, Liu, Guoshi, Li, Xiang, Yang, Liguo, He, Changjiu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102596/
https://ncbi.nlm.nih.gov/pubmed/33958705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02042-z
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