Melatonin delays ovarian aging in mice by slowing down the exhaustion of ovarian reserve

Studies have shown that melatonin (MLT) can delay ovarian aging, but the mechanism has not been fully elucidated. Here we show that granulosa cells isolated from mice follicles can synthesize MLT; the addition of MLT in ovary culture system inhibited follicle activation and growth; In vivo experimen...

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Pubblicato in:Commun Biol
Autori principali: Yang, Chan, Liu, Qinghua, Chen, Yingjun, Wang, Xiaodong, Ran, Zaohong, Fang, Fang, Xiong, Jiajun, Liu, Guoshi, Li, Xiang, Yang, Liguo, He, Changjiu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102596/
https://ncbi.nlm.nih.gov/pubmed/33958705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02042-z
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