Melatonin delays ovarian aging in mice by slowing down the exhaustion of ovarian reserve

Studies have shown that melatonin (MLT) can delay ovarian aging, but the mechanism has not been fully elucidated. Here we show that granulosa cells isolated from mice follicles can synthesize MLT; the addition of MLT in ovary culture system inhibited follicle activation and growth; In vivo experimen...

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Bibliografiske detaljer
Udgivet i:Commun Biol
Main Authors: Yang, Chan, Liu, Qinghua, Chen, Yingjun, Wang, Xiaodong, Ran, Zaohong, Fang, Fang, Xiong, Jiajun, Liu, Guoshi, Li, Xiang, Yang, Liguo, He, Changjiu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102596/
https://ncbi.nlm.nih.gov/pubmed/33958705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02042-z
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