The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

Low protein diets promote metabolic health in rodents and humans, and the benefits of low protein diets are recapitulated by specifically reducing dietary levels of the three branched-chain amino acids (BCAAs), leucine, isoleucine, and valine. Here, we demonstrate that each BCAA has distinct metabol...

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Publicado no:Cell Metab
Main Authors: Yu, Deyang, Richardson, Nicole E., Green, Cara L., Spicer, Alexandra B., Murphy, Michaela E., Flores, Victoria, Jang, Cholsoon, Kasza, Ildiko, Nikodemova, Maria, Wakai, Matthew H., Tomasiewicz, Jay L., Yang, Shany E., Miller, Blake R., Pak, Heidi H., Brinkman, Jacqueline A., Rojas, Jennifer M., Quinn, William J., Cheng, Eunhae P., Konon, Elizabeth N., Haider, Lexington R., Finke, Megan, Sonsalla, Michelle, Alexander, Caroline M., Rabinowitz, Joshua D., Baur, Joseph A., Malecki, Kristen C., Lamming, Dudley W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102360/
https://ncbi.nlm.nih.gov/pubmed/33887198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2021.03.025
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