The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

Low protein diets promote metabolic health in rodents and humans, and the benefits of low protein diets are recapitulated by specifically reducing dietary levels of the three branched-chain amino acids (BCAAs), leucine, isoleucine, and valine. Here, we demonstrate that each BCAA has distinct metabol...

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Библиографические подробности
Опубликовано в: :Cell Metab
Главные авторы: Yu, Deyang, Richardson, Nicole E., Green, Cara L., Spicer, Alexandra B., Murphy, Michaela E., Flores, Victoria, Jang, Cholsoon, Kasza, Ildiko, Nikodemova, Maria, Wakai, Matthew H., Tomasiewicz, Jay L., Yang, Shany E., Miller, Blake R., Pak, Heidi H., Brinkman, Jacqueline A., Rojas, Jennifer M., Quinn, William J., Cheng, Eunhae P., Konon, Elizabeth N., Haider, Lexington R., Finke, Megan, Sonsalla, Michelle, Alexander, Caroline M., Rabinowitz, Joshua D., Baur, Joseph A., Malecki, Kristen C., Lamming, Dudley W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102360/
https://ncbi.nlm.nih.gov/pubmed/33887198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2021.03.025
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