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Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors
The metabotropic glutamate receptors (mGluRs) form a family of neuromodulatory G-protein-coupled receptors that contain both a seven-helix transmembrane domain (TMD) and a large extracellular ligand-binding domain (LBD) which enables stable dimerization. Although numerous studies have revealed varia...
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| Publicado en: | eLife |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8102066/ https://ncbi.nlm.nih.gov/pubmed/33880992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.67027 |
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