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Chronic loss of inhibition in piriform cortex following brief, daily optogenetic stimulation

It is well established that seizures beget seizures, yet the cellular processes that underlie progressive epileptogenesis remain unclear. Here, we use optogenetics to briefly activate targeted populations of mouse piriform cortex (PCx) principal neurons in vivo. After just 3 or 4 days of stimulation...

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Publicado en:Cell Rep
Autores principales: Ryu, Brendan, Nagappan, Shivathmihai, Santos-Valencia, Fernando, Lee, Psyche, Rodriguez, Erica, Lackie, Meredith, Takatoh, Jun, Franks, Kevin M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102022/
https://ncbi.nlm.nih.gov/pubmed/33882304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109001
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