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Chronic loss of inhibition in piriform cortex following brief, daily optogenetic stimulation

It is well established that seizures beget seizures, yet the cellular processes that underlie progressive epileptogenesis remain unclear. Here, we use optogenetics to briefly activate targeted populations of mouse piriform cortex (PCx) principal neurons in vivo. After just 3 or 4 days of stimulation...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ryu, Brendan, Nagappan, Shivathmihai, Santos-Valencia, Fernando, Lee, Psyche, Rodriguez, Erica, Lackie, Meredith, Takatoh, Jun, Franks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102022/
https://ncbi.nlm.nih.gov/pubmed/33882304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109001
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