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Chronic loss of inhibition in piriform cortex following brief, daily optogenetic stimulation

It is well established that seizures beget seizures, yet the cellular processes that underlie progressive epileptogenesis remain unclear. Here, we use optogenetics to briefly activate targeted populations of mouse piriform cortex (PCx) principal neurons in vivo. After just 3 or 4 days of stimulation...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Ryu, Brendan, Nagappan, Shivathmihai, Santos-Valencia, Fernando, Lee, Psyche, Rodriguez, Erica, Lackie, Meredith, Takatoh, Jun, Franks, Kevin M.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102022/
https://ncbi.nlm.nih.gov/pubmed/33882304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109001
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