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Origin and evolution of the zinc finger antiviral protein
The human zinc finger antiviral protein (ZAP) recognizes RNA by binding to CpG dinucleotides. Mammalian transcriptomes are CpG-poor, and ZAP may have evolved to exploit this feature to specifically target non-self viral RNA. Phylogenetic analyses reveal that ZAP and its paralogue PARP12 share an anc...
Gorde:
| Argitaratua izan da: | PLoS Pathog |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8102003/ https://ncbi.nlm.nih.gov/pubmed/33901262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009545 |
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