Colonization of the Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate

Protein conformational diseases are characterized by misfolding and toxic aggregation of metastable proteins, often culminating in neurodegeneration. Enteric bacteria influence the pathogenesis of neurodegenerative diseases; however, the complexity of the human microbiome hinders our understanding o...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Walker, Alyssa C., Bhargava, Rohan, Vaziriyan-Sani, Alfonso S., Pourciau, Christine, Donahue, Emily T., Dove, Autumn S., Gebhardt, Michael J., Ellward, Garrett L., Romeo, Tony, Czyż, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101752/
https://ncbi.nlm.nih.gov/pubmed/33956916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009510
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