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The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease

The presence of only small amounts of misfolded protein is an indication of a healthy proteome. Maintaining proteome health, or more specifically, “proteostasis,” is the purview of the “proteostasis network.” This network must respond to constant fluctuations in the amount of destabilized proteins c...

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Bibliographic Details
Published in:Biol Direct
Main Author: Kikis, Elise A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093949/
https://ncbi.nlm.nih.gov/pubmed/27809888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-016-0161-2
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