Colonization of the Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate

Protein conformational diseases are characterized by misfolding and toxic aggregation of metastable proteins, often culminating in neurodegeneration. Enteric bacteria influence the pathogenesis of neurodegenerative diseases; however, the complexity of the human microbiome hinders our understanding o...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Walker, Alyssa C., Bhargava, Rohan, Vaziriyan-Sani, Alfonso S., Pourciau, Christine, Donahue, Emily T., Dove, Autumn S., Gebhardt, Michael J., Ellward, Garrett L., Romeo, Tony, Czyż, Daniel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101752/
https://ncbi.nlm.nih.gov/pubmed/33956916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009510
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