Colonization of the Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate

Protein conformational diseases are characterized by misfolding and toxic aggregation of metastable proteins, often culminating in neurodegeneration. Enteric bacteria influence the pathogenesis of neurodegenerative diseases; however, the complexity of the human microbiome hinders our understanding o...

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Vydáno v:PLoS Pathog
Hlavní autoři: Walker, Alyssa C., Bhargava, Rohan, Vaziriyan-Sani, Alfonso S., Pourciau, Christine, Donahue, Emily T., Dove, Autumn S., Gebhardt, Michael J., Ellward, Garrett L., Romeo, Tony, Czyż, Daniel M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101752/
https://ncbi.nlm.nih.gov/pubmed/33956916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009510
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