Emulated Clinical Trials from Longitudinal Real-World Data Efficiently Identify Candidates for Neurological Disease Modification: Examples from Parkinson’s Disease

Real-world healthcare data hold the potential to identify therapeutic solutions for progressive diseases by efficiently pinpointing safe and efficacious repurposing drug candidates. This approach circumvents key early clinical development challenges, particularly relevant for neurological diseases,...

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Pubblicato in:Front Pharmacol
Autori principali: Laifenfeld, Daphna, Yanover, Chen, Ozery-Flato, Michal, Shaham, Oded, Rosen-Zvi, Michal, Lev, Nirit, Goldschmidt, Yaara, Grossman, Iris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100658/
https://ncbi.nlm.nih.gov/pubmed/33967767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.631584
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